Endocrine Abstracts

Insulin replacement therapy is essential for anyone with type 1 diabetes. Most patients with gestational or type 2 diabetes may also require insulin. The goals of insulin therapy are: to achieve optimal glycemic control without causing hypoglycemia or excessive weight gain and to minimize the impact on lifestyle. The therapeutic goals should be individualized according to patient’s age, disease duration, complications, comorbidities, lifestyle, and expected survival.<...

Hypoglycaemia is associated with considerable morbidity and even mortality in type 1, and less likely in type 2 diabetes. Generally, hypoglycaemia is accepted as a surrogate marker of poor health as it is likely to be more prevalent in renal and liver failures, which independently increase cardiovascular diasease (CVD) and neurocognitive risks. Hypoglycaemia, have been implicated with a fortunately rare but tragic event, ‘dead-in-bed’ syndrome. It has been hypothesis...

Objective: Our purpose was to evaluate the impact of a transmission system on metabolic control of patients with diabetes.Research design and methods: This ongoing-prospective, randomized, comparative study included adult patients with type 1 (n=71) and type 2 diabetes (n=139). Consecutive patients were equally allocated into two groups. Both groups received routine care by the same health care professionals (HCPs) 3-monthly. TeleDiab g...

Background: Clinical practice guidelines on diabetes mellitus (DM) have been developed in 2006 by The Society of Endocrinology and Metabolism of Turkish (SEMT). The ongoing ADMIRE Project is designed to evaluate the effect of implementation of various activities to increase the awareness of physicians on the adherence to SEMT guidelines. The first phase results of the project is presented.Methods: Of 180 physicians evaluated previous 12 months’ medi...

Introduction: Diabetic patients have an increased risk of developing dementia and cognitive impairments. DM related factors such as macrovascular and microvascular complications, glucose toxicity, hyperinsulinemia have been suggested to be involved cognitive impairment even in prediabetic stage. Our aim is to establish the relationship between insulin resistance and cognitive impairment and the effect of poorly controlled diabetes on cognitive impairment.<p class="abstext"...

Introduction: The accurate and comprehensive assessment of glycaemic control in pregnant with gestational diabetes (GDM) is important for preventing foetal complications. We aimed to determine glycaemic variation on women with GDM with using a continuous glucose monitoring system (CGMS) and to investigate the relationship between reflecting glucose markers such as HbA1c, fructosamine (FRM), and 1,5-anhydroglucitol (1,5-AG).Materials and methods: 31 women...

Enormous evidence suggests that vitamin D deficiency could be linked to several chronic diseases, including cardiovascular disease, diabetes, obesity, depression and cancer. The purpose of this study was to examine the prevalence of vitamin D deficiency and its correlates to test the hypothesis that vitamin D deficiency was common among adult Turkish population, particularly in women. The Turkish Diabetes, Hypertension, Obesity and Endocrine Disease Survey (TURDEP-II) Jan to J...

Introduction: Type 1 diabetes mellitus (T1DM) requires lifelong management, and a well-designed protocol may facilitate transition from child-centered healthcare systems to adult-oriented systems.Aim: We aimed to evaluate sociodemographic data, clinical features and laboratory parameters that may affect the transition period and post-transition process in T1DM patients.Materials and Methods: We retrospectively analyzed 64 patients ...

Objective: Establishing good metabolic control is essential to prevent morbidity and mortality in patients with type 2 diabetes (T2DM). This nationwide survey is performed five years after the first national TEMD study, to search for any improvement in attaining glycemic and metabolic targets in Turkish patients with T2DM.Methods: The nationwide, multicenter survey consecutively enrolled patients who were under follow up for at least a year in tertiary c...

Background and objectives: Diabetes is estimated to affect more than half a billion people worldwide, of which approximately 9.5 million live in Turkey. Currently, glucoSemeasurements are made with invasive techniques (eg finger puncture or interstitial glucose sensors) that can negatively affect monitoring. In addition, since glucose results cannot be seen by physicians/nurses in real time, treatment decisions are delayed and diabetes control becomes difficult. As a group of ...